BENZALKONIUM CHLORIDE Quaternary Ammonium Compounds (e.g. Overview. These are chemicals that serve the purpose to act as an antimicrobial and a surfactant in various shampoo products. Now there’s a new generation of non-alcohol hand sanitizers, most of which contain the active ingredient benzalkonium chloride. BenzalkoniumBenzalkonium ChlorideDo Hand Sanitizer Lotions Actually Work? | Everyday HealthIn Vitro Evaluation of Mitochondrial Function and Estrogen ...Avoid These 115 Hand Sanitizers, F.D.A. Warns - The New ... Benzalkonium chloride shows different results in NHEK and NB1RGB cell cultures, and the ED50 of 3.9 and 62 μM, respectively. Reactivity Profile. OR. Benzalkonium chloride is a topical antiseptic and antibacterial agent used to prevent infection of wounds and minor burns, as well as for the treatment of cold sores and fever blisters. Use 4 Hour Protection™ benzalkonium chloride hand sanitizer to fight 99% of the most common germs and proven effective... AJOG's Editors have active research programs and, on occasion, publish work in the Journal. Benzalkonium Chloride is one of a handful of recognised actives for alcohol-free hand and surface sanitisation, you can look up others by following link 12 (below) which gives a list of EPA approved products based on their actives. Packaged for single use. Sensitive to light. Adv Ther 2011;28:501-10. Antimicrobial quaternary ammonium salts (QUATS) compounds, such as cetylpyridinium chloride (CPC) and benzalkonium chloride (BAK), have been used in personal care products, such as soaps and body washes, until the recent U.S. Food and Drug Administration (FDA) ruling (), and are currently being used in hand lotions, toothpastes, … Benzethonium chloride is a (synthetic) quaternary ammonium salt that is benzyldimethylamine in which the nitrogen is quaternised by a 2-{2-[p-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy}ethyl group, with chloride as the counter-ion. Tumor Marker ELISA Kits . BENZETHONIUM CHLORIDE is incompatible with strong oxidizing agents. Cancer lists Ingredient Known Carcinogenicity? Price. BENZETHONIUM CHLORIDE is incompatible with strong oxidizing agents. I have a bit of a history with this chemistry. Similarly, benzalkonium chloride caused death of bovine articular chondrocytes, bovine synovial cells, C3H10T1/2 cells, and MG-63 cells in a dose-dependent manner. : AC263820000; AC263820010; AC263820025 Synonyms Alkyl-benzyl-dimethylammonium chloride Recommended Use Laboratory chemicals. Tell your doctor if you are pregnant or plan on getting pregnant. Monoclonal Antibodies . Benzalkonium chloride (BAC) is a preservative used in albuterol and metaproterenol nebulizer solutions in the United States and in beclomethasone and ipratropium nebulizer solutions in other countries (see Box 80.8). Zephiran Chloride is an antiseptic solution used to cleanse the skin after minor scrapes, cuts and burns. We're growing! 79,80 It is cationically charged and induces antibacterial action through attraction to the negatively charged bacterial membrane. Shampoo is a basic hair care product representing the largest segment of hair care cosmetics. The F.D.A. Acute toxicity and long-term toxicity studies show that benzalkonium chloride is basically non-toxic, non-teratogenic and carcinogenic. It works by killing microorganisms and inhibiting their future growth, and for this reason frequently appears as an ingredient in antibacterial hand wipes, antiseptic creams and anti-itch ointments. Date of Listing: 01/01/1990. Do not use this medicine with disinfectants containing quaternary ammonium salts (e.g., benzalkonium chloride). Appearance:contact us for more details about BENZALKONIUM CHLORIDE, CAS:63449-41-2 Einecs: 264-151-6 Description: FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. Get medical attention if symptoms persist. European Medicines Agency - For help on how to get the results you want, see our search tips. Cetylpyridinium Chloride. Benzalkonium chloride (BAK) Benzalkonium chloride (BAK) is the most common preservative in topical medication used to treat glaucoma [10R, 11R]. Dodecyl and tetradecylpyridinium chloride, were biodegraded in the Spanish official test (93 and 94%, respectively) and in the OECD Confirmatory test (91 and 92%, respectively). The mixture of … Growth inhibition of alga P. subcapitata after exposure to the binary mixture of benzalkonium chloride [BAC] and 5-fluorouracil [5-FU]. In Canada, it is a known active ingredient in hard surface disinfectants and hand sanitizers. Scientific discussion 1. Add Resources to Your List. Yoko Goto, MD; Nobuhiro Ibaraki, MD, PhD; Kensaku Miyake, MD. 5. This may cause harmful gases. The American Cancer Society looks to these organizations to evaluate the risks based on evidence from laboratory, animal, and human research studies. Reactivity Profile. 8001-54-5 - Benzalkonium chloride [INN:BAN:JAN:NF] - Similar structures search, synonyms, formulas, resource links, and other chemical information. Inactive Ingredients: Benzalkonium chloride, boric acid, edetate disodium, purified water, sodium borate, sodium chloride, sodium hydroxide, and/or hydrochloric acid; Which Eye Drop is Best for You? NTP? January 8, 2021 / December 28, 2021 by Clete Campbell. Anticipated? This information explains how to collect a urine (pee) sample using the clean catch urine collection method. Amazon.com: Dynarex Antiseptic Wipe Benzalkonium BZK First ... best www.amazon.com. Benzalkonium Chloride) Version 1.1 Revision Date: 02/06/2020 SDS Number: N00109155406 Date of last issue: 01/29/2020 Date of first issue: 01/29/2020 SECTION 1. WebMD provides common contraindications for benzalkonium chloride. When treated with a combination of betamethasone sodium phosphate and 200 μg/mL benzalkonium chloride, >99% of human or bovine articular chondrocytes were dead (p < 0.001). benzalkonium chloride, tetraethylammonium bromide ) Prothrombin concentrates / complexes. Description:Physical and chemical properties of benzalkonium chloride The density of 0.989 g/cm3 Boiling point 100 DHS C Melting point - 5 DHS C Molecular formula C22H40ClN Updatetime: Nov 27 2020 more + Benzalkonium chloride is a well-known irritant [1]. We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production. First-Aid Measures General Advice: Take proper precautions to ensure your own health and safety before attempting rescue and providing first aid. Log in to print or send this list to your patient and save lists of resources you use frequently. Acute toxicity - Oral, Category 4 Acute toxicity - Dermal, Category 4 Skin corrosion, Category 1B Find out what health conditions may be a health risk when taken with benzalkonium chloride Production. 65 Components This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm. Benzalkonium chloride (BC) is a common disinfectant widely used in food industry. Shop our full range of hand sanitiser and antibacterial hand gels available online at Boots. Some studies have shown that without these contaminants, a truly natural extract of grapefruit seed and pulp in ethanol or glycerin, had no antibacterial properties. Benzalkonium Chloride. As many long-time readers may know, I… ammonium chloride 4.50% Octyl decyl dimethyl ammonium chloride 3.38% Didecyl dimethyl ammonium chloride 1.68% Dioctyl dimethyl ammonium chloride 1.68% n-Alkyl (50% C 14, 40% C 12, 10% C 16) dimethyl benzyl ammonium chloride 2.25% Octyl decyl dimethyl ammonium chloride 1.69% Didecyl dimethyl ammonium chloride 0.84% Dioctyl … In 1978 the experimental model of myenteric denervation of the rat gut by serosal application of benzalkonium chloride (BAC) was proposed. Bleach is a basic solution. Acids cause it to precipitate from aqueous solutions of >2% concentration. This may prevent hyaluronic acid injection from working properly. Hives. Benzalkonium chloride topical Side Effects. Buy Benzalkonium Chloride, CAS number: 8001-54-5, online for pharmaceutical analytical testing. Some studies have shown that without these contaminants, a truly natural extract of grapefruit seed and pulp in ethanol or glycerin, had no antibacterial properties. The chemical was selected based on a suspicion of carcinogenicity and its known widespread human exposure. OBJECTIVE: To investigate the short-term impact on human conjunctival goblet cell (GC) survival and mucin release of acute exposure to benzalkonium chloride (BAK) preserved and preservative-free (PF) 0.005% (w/v) latanoprost … Benzalkonium chloride adalah zat amonium yang bisa ditemukan dalam produk antiseptik dan disinfektan. If someone has overdosed and has serious symptoms such as passing out or trouble breathing , call 911. The C12-18 (carbon chain which is 12-18 carbon atoms in length) part of the name indicates the presence of alkyl groups 'Lauric (C12)', 'Tridecyclic (C13)', 'Myristic (C14)', 'Pentadecanoic (C15)', 'Palmitic (C16)', 'Margaric (C17)' and/or 'Stearic (C18)'. Benzalkonium chloride (BAC) is one of the most common ingredients of the disinfectants. Benzalkonium Chloride is sold commercially as 50.0% or 80.0% solutions in water or alcohol, or in mixtures of water, ethyl alcohol, and isopropyl alcohol.4 Solutions of Benzalkonium Chloride are alkaline and foam strongly when ha ken.^ Benzalkonium Chloride, in water or in methanol, has an ultraviolet Seamless Bandana. Section 16 - Other Information Sisco Research Laboratories Pvt. Medically reviewed by Drugs.com. Answer (1 of 2): No, because benzalkonium chloride contains nitrogen. Ingestion Seek medi cal advi e. Most important For personal hygiene at every napkin change and whenever cleansing/refreshing is needed. Our network of … Regular use of products containing antimicrobials such as benzalkonium chloride could leads to the development of resistant bacteria in homes and food processing facilities. Benzalkonium chloride There’s strong evidence that this antibacterial ingredient is linked to allergy problems in humans, including severe skin, eye and respiratory irritation. Incompatible with soap and anionic detergents. Can react with nitrates. Next up on the toxic ingredient shampoo list we have two different types of Chlorides, Benzalkonium Chloride and Benzethonium Chloride. Environmental Working Group notes this ingredient is considered especially dangerous to people with skin conditions like eczema. Benzalkonium chloride (BAC), benzethonium chloride (BET), and chloroxylenol (PCMX) are chemicals used in high-volume as antimicrobial and antibacterial ingredients in many consumer, industrial, and medical products, including eye and nasal drops, soaps, mouthwash, and cosmetics (see chemical structures of these compounds in Figure 1).Previous studies … Benzalkonium chloride (BKC) is a quaternary ammonium antimicrobial agent included in some nasal solns. Benzalkonium chloride in eye drops has also been reported to cause punctate keratopathy and/or toxic ulcerative keratopathy, especially in frequent or prolonged use or in conditions where the cornea is compromised. Patients who wear soft contact lenses and whose eyes are not red should be instructed to wait at least ten minutes after instilling PATANOL (olopatadine hydrochloride ophthalmic solution) 0.1% before they insert their contact lenses. Benzethonium Chloride and Methylbenzethonium Chloride occur as color- less to white, odorless to mildly odorous, and bitter tasting monohydrate crystals. Pharmacy. No one drop is best for all patients. In principle, there are two things that you do not want to mix with bleach: 1. Research. BENZALKONIUM CHLORIDE. DSS for Colitis and IBD Research. Among quats, Benzalkonium Chloride has been known to have the most impact on natural hormone function disruption and causing reproductive toxicity. Keep container tightly sealed,avoid contact with eyes ,wash hands after handing,not for use on broken or sensitive skin,stop use if skin irritation develops,flush eyes immediately if product enters eyes.Keep away from heat and flame.Call a poison control center or doctor for treatment advice.Have the product container label with you when calling a poison … Human Lens Epithelial Cell Damage and Stimulation of Their Secretion of Chemical Mediators by Benzalkonium Chloride Rather Than Latanoprost and Timolol. Biocide, preservative and surfactant associated with severe skin, eye, and respiratory irritation and allergies, benzalkonium chloride is a sensitizer especially dangerous for people with asthma or skin conditions such as eczema. Development. Contains antiseptic benzalkonium chloride solution Helps prevent infection in minor cuts, scraps and burns Ideal for gentle antiseptic cleansing without soap and water Individually wrapped 5" x 7" towelette Box of 100 New (8) from $6.30 & FREE Shipping Special offers and product promotions Incompatible with soap and anionic detergents. Product Name Benzalkonium chloride, 50 wt% aqueous solution Cat No. (including glucocorticosteroids) to prevent the growth of bacteria. Other potential benzethonium chloride … Peptide analogs. Benzalkonium chloride has repeatedly demonstrated its toxic characteristics in laboratory, experimental, and clinical studies. Benzalkonium chloride solutions are fast-acting biocidal agents with a moderately long duration of action. They are active against bacteria and some viruses, fungi, and protozoa. Bacterial spores are considered to be resistant. 2. In the topical version, the potential side-effects and warnings are as follows: Signs of an allergic reaction such as a skin Rash. NDC Code (s): 54622-148-20. Instead of alcohol, some hand sanitizers contain quaternary ammonium compounds (notably benzalkonium chloride or benzethonium chloride) to reduce microbes. These agents are less effective than alcohol, plus they lack evidence of real-life benefits. Stable for two weeks at temperatures up to 140 F, (NTP, 1992). Using this method helps keep germs on the skin around your urinary opening (the hole where urine leaves your body) from getting into the urine sample. 6. Parabens are known to stimulate cancer cells at high doses in the short-term, but it’s still not clear if low-dose accumulation can cause cancer in humans [14]. Based on animal and human evidence, several expert agencies have evaluated the cancer-causing potential of benzene. The clinically used concentration (0.01% Benzalkonium chloride) significantly reduces cell viability, with only 14%-19% of nasal epithelial cells surviving the treatment[1]. Aluminium chlorohydrate is a group of water-soluble, specific aluminum salts having the general formula Al n Cl (3n-m) m.It is used in cosmetics as an antiperspirant and as a coagulant in water purification.. Alterations of choline phospholipid metabolism in tumor progression have been reported , thereby possibly accounting for the cancer specificity of benzethonium chloride. Avoid wearing lenses with signs and symptoms of … Check out our job openings! Find patient medical information for ofloxacin ophthalmic (eye) on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Benzalkonium Chloride is primarily used as a preservative and antimicrobial agent, and secondarily used as a surfactant. Overdose. Benzalkonium Chloride: 0.004%: Vehicle Amount; Hypromellose 2910: 0.5%: Other Ingredients: Sodium Chloride, Polysorbate 20, Purified Water * May contain Hydrochloric Acid and/or Sodium Hydroxide to adjust pH. In the topical version, the potential side-effects and warnings are as follows: Signs of an allergic reaction such as a skin Rash. Zhang R, Park M, Richardson A, et al. When benzalkonium chloride comes into contact with the skin, it can cause irritant contact dermatitis or allergic contact dermatitis in some individuals. Benzalkonium chloride sering digunakan sebagai campuran dalam berbagai produk obat, seperti obat tetes mata, obat tetes telinga, atau semprot hidung. Some reports suggest that BKC in nasal sprays may cause adverse effects, including reduced mucociliary transport, rhinitis medicamentosa, and neutrophil dysfunction. Ltd. provides the information contained herein in good faith but makes no Use of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be reproduced, distributed and/or used, totally or in part, for non-commercial purposes … Benzalkonium chloride is a well-known irritant [1]. Regarding their addition to intranasal products, a review of 18 studies from the literature revealed no major safety concerns when BACs were used in concentrations ranging from 0.00045% to 0.1% (23). to Timolol Maleate IP + Benzalkonium chloride solution IP (as preservative) + Water for injection IP q.s. Selective pressure associated with exposure to BC may result in adaptation to this agent in L. monocytogenes. (A substance that causes cancer or helps cancer grow is called a carcinogen.) Prostate cancer cells have downregulated ZIP1 transporters which leads to greater ATP generation which is diverted to cancer proliferation, an example of a normal-like metabolic phenotype instead being malignant. The invention relates to a method of photoeradication of cellular and acellular organisms including the steps of providing a surface acting agent containing benzalkonium chloride in association with a cellular or acellular organism, the surface acting agent disorienting a membrane structure so that said membrane no longer functions as an effective osmotic barrier; providing a … Next up on the toxic ingredient shampoo list we have two different types of Chlorides, Benzalkonium Chloride and Benzethonium Chloride. ; Anal itching also can be caused by the irritation of continuous moisture in the anus from frequent liquid stools, diarrhea, or escape of small amounts of stool (incontinence or fecal spoilage). Quantity. The biggest contaminant found is benzalkonium chloride, a chemical that rates a 7 in the cosmetics database that's a known immune system toxin, skin toxin, and possible cancer risk. Full Text. Glaucoma benzalkonium chloride Free products Glaucoma Preservative-Free drops. eCollection 2021. WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov. May be absorbed by soft contact lenses. Breast Cancer Awareness Patriotic Campaign Trail Pets & Animals Charity Walks/Events Police Colleges and Universities Politics ... Benzalkonium Chloride Inact. Antidepressant discontinuation syndrome ... Prostate Cancer. Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia ABSTRACT Background. It can be difficult to determine the cancer risk of an ingredient, with the FDA and EU frequently coming to different conclusions. The minimum inhibitory concentrations (MICs) of 60 meticillin-resistant Staphylococcus aureus (MRSA) isolates from Malaysia to three antiseptic agents - benzalkonium chloride (BZT), benzethonium chloride (BAC) and chlorhexidine digluconate (CHG) - were determined. Psoriasis. You will need to talk about the benefits and risks of using benzalkonium chloride while you are pregnant. Listeria monocytogenes is an important food-borne pathogen that can persist in food processing environments and thus contaminate food products. Multi-center studies suggest that benzalkonium chloride is safe for maternal, infant and young children. The highest quality reference standards for reliable results. In the present study, human … Introduction. doi: 10.1136/bmjophth-2021-000892. Never mix cleaning products. Benzethonium chloride is used primarily in cosmetics for its antimicrobial and cationic surfactant properties. Cancer; Listed as causing: Cancer. Castor oil is a common component in some artificial tears solutions. Chemical Listing Details. Benzalkonium chloride is primarily used as a preservative and antimicrobial agent. The clinically used concentration (0.01% Benzalkonium chloride) significantly reduces cell viability, with only 14%-19% of nasal epithelial cells surviving the treatment[1]. Sensitive to light. Benzalkonium Chloride and Benzocaine. DEA Schedule: None. Acids cause it to precipitate from aqueous solutions of >2% concentration. There is a problem with information submitted for this request. Irritant contact dermatitis due to benzalkonium chloride is more common than allergic contact dermatitis from its use. BAK is well documented to be toxic to the epithelial cells of the eyes. Tell your doctor if you are breast-feeding. Label: HAND SANITIZER- benzalkonium chloride 0.1%w/w liquid. They had discovered a COVID-19-neutralizing revelation. once again, with Benzalkonium Chloride, we’re looking at the topical version of this chemical, which is also present in some mouthwash brands. Uses advised against Food, drug, pesticide or biocidal product use. BENZALKONIUM CHLORIDE. Scary Shampoo Ingredient #5: Benzalkonium Chloride and Benzethonium Chloride. Itching. The preservative in PATANOL (olopatadine) , benzalkonium chloride, may be absorbed by soft contact lenses. Safe Harbor Levels; Cancer: No Significant Risk Level (NSRL): 4 µg/day. Benzethonium chloride damages phospholipid membranes and may possibly affect α 7 and α 4 β 2 neuronal nicotinic acetylcholine receptors (48, 49). Benzalkonium chloride 344 mg/kg (rat) >2000 mg/kg (rabbit) 0.054 - 0.51 mg/l mist The product is non-toxic by ingestion or inhalation. Cal EPA. Label: HAND SANITIZER- benzalkonium chloride 0.1%w/w liquid. Benzalkonium chloride (BAC) is a wide spectrum quaternary ammonium antibacterial agent that has been used in various dental composites. An itchy bottom can be caused by irritating chemicals in the foods we eat, such as are found in spices, hot sauces, and peppers. Editor/authors are masked to the peer review process and editorial decision-making of their own work and are not able to access this work in … All products mentioned contain benzalkonium chloride. A risk assessment of benzalkonium chloride (BAC) was conducted based upon its toxicological profile and exposure evaluation. Alkyl(C12-18)Dimethyl Ethylbenzyl Ammonium Chloride is a family of compounds similar to Benzalkonium chloride. Each box contains 100 individually wrapped wipes. Benzyl Chloride; Benzyl Chloride . IDENTIFICATION Product name : Scott ® Control Antimicrobial Foam Skin Cleanser (0.1% Benzalkonium Chloride) Product code : 91554 Manufacturer or supplier's details Zat ini bekerja dengan cara menghentikan pertumbuhan beberapa jenis bakteri, virus, dan jamur. This compound is known to cause extensive damage to the eyes, such as tear film instability, loss of goblet cells, conjunctival squamous metaplasia, apoptosis, damage to deeper ocular tissues, and disruption of the corneal … Although cell membrane damage has been considered as the main cytotoxic mechanism of BAC, its concentration- and time-dependent cellular effects on lung epithelium have not been fully understood. Pulmonary fibrosis (idopathic) -(IPF) Pulmonary Hypertension. BMJ Open Ophthalmol. Category (function) Benzalkonium chloride is a quaternary amm onium antiseptic and disinfectant with actions and uses similar to those of other cationic surfactants. Benzethonium chloride (0.027 g/601) + Benzalkonium chloride (0.0405 g/601) + Bronopol (0.0405 g/601) + Ethanol (101.25 g/601) + Phenoxyethanol (0.081 g/601) Cloth: Topical: Baijieyuan Biotechnology (Shandong) Co., Ltd. 2020-06-10: Not applicable: US: Aiweier Disinfecttant Wipes also flagged several more products that had inadequate amounts of benzalkonium chloride, a chemical with antimicrobial properties. per ml Ophthalmic Suspension (Phase III) … Benzalkonium chloride is an anti-bacterial cationic surfactant. Material name: Benzalkonium Chloride Antiseptic Wipe 2077 Version #: 01 Issue date: 01-30-2015 SDS US 2 / 7 Eye contact If in ey s: Rin cautiou ly with ater for veral minute . Benzalkonium chloride is found in many household disinfectants and cleaning supplies. Basis for Listing: AB-IARC. Benzalkonium chloride shows different results in NHEK and NB1RGB cell cultures, and the ED50 of 3.9 and 62 μM, respectively. An antiseptic and disinfectant, it is active against a broad spectrum of bacteria, fungi, moulds and viruses. Three broad-spectrum actives, ethanol, isopropanol and benzalkonium chloride (BZK), are allowed under the current FDA OTC Hand Sanitizer monographs for healthcare workers and consumers. Benzethonium Chloride, when crystallized from benzene, chloroform, or ether, forms thin hexagonal plates. Protease Inhibitors. Otherwise, call a … Chemical Status; Cancer: Currently listed. Packager: Georgia Pacific Consumer Products. Benzalkonium Chloride. An antiseptic and disinfectant, it is active against a broad spectrum of bacteria, fungi, moulds and viruses. Benzalkonium Chloride, Alcohol-Free Sanitizer Just as Effective at Fighting COVID-19. May be absorbed by soft contact lenses. More information about Benzyl Chloride. From complete isolation kits that simplify your workflows to individual reagents, we make it easy to get high-quality DNA and RNA from even difficult-to-lyse samples. In 2016, the U.S. Food and Drug Administration removed 19 antimicrobial ingredients from consumer antiseptic … We use cookies to ensure that we give you the best experience of our website. Using it helps to lubricate the eyes and prevent moisture from leaving the … When benzalkonium chloride comes into contact with the skin, it can cause irritant contact dermatitis or allergic contact dermatitis in some individuals. In summary, many lubricating drops are available over-the-counter and have different formulations. IARC Category Benzalkonium chloride No No No None Section XII - Ecological Information This product is not expected to bioaccumulate. This is an allergen that can cause irritations in the skin and mucous membranes, leading to allergic reactions, difficulty breathing, and swelling of the mouth, face, lips or tongue. Experimental denervation of organs plays a key role in understanding the functional aspects of the normal innervation as well as the diseases related to them. Benzalkonium Chloride and Benzocaine - Last updated on October 20, 2021 All rights owned and reserved by Memorial Sloan Kettering Cancer Center. Apply now! Effects of benzalkonium chloride- and polyquad-preserved combination glaucoma medications on cultured human ocular surface cells. Both regulatory bodies review reports published by the World Health Organization’s (WHO) independent ‘International Agency for Research on Cancer’ (IARC), which classifies compounds into five categories of Clinically, benzalkonium chloride may cause eye irritation and is known to discolour soft contact lenses. Show this safety data sheet to the doctor in attendance. once again, with Benzalkonium Chloride, we’re looking at the topical version of this chemical, which is also present in some mouthwash brands. Cell Culture Reagents for Cancer Research . Educational Resources. The frequent, daily use of hand sanitizers containing 0.3% benzalkonium chloride may cause red, itchy, dry or scaly skin in susceptible individuals. Quickly generate murine models of intestinal inflammatory diseases using our high-quality, high-purity dextran sulfate sodium (DSS).